WebNov 14, 2013 · Next, central motif enrichment analysis will determine if other known DNA motifs are enriched near the centers (or summits) of the ChIP-seq peaks . It can also be useful to perform local motif enrichment analysis on regions centered on genomic landmarks such as transcription start sites overlapped by ChIP-seq peaks [61] . WebApr 5, 2024 · ChIP-Seq analysis results suggested that the proximal altered H3K4me3 regions were located at differentially expressed genes involved in cancer-related pathways, while altered distal H3K4me3 regions were annotated with enhancer activity of cancer regulatory genes. ... Our KEGG pathway enrichment analysis on the DEGs from our …
ChIP-Enrich: gene set enrichment testing for ChIP-seq data
WebOct 24, 2024 · HOMER (v4.11, 10-24-2024) Software for motif discovery and next generation sequencing analysis HOMER (Hypergeometric Optimization of Motif … WebJun 15, 2016 · Chromatin immunoprecipitation followed by next-generation sequencing (ChIP-seq) is a key technique for mapping the distribution and relative abundance of histone posttranslational modifications ... literary cartography
National Center for Biotechnology Information
WebModel-based analysis of ChIP-seq (MACS) is a computational algorithm that identifies genome-wide locations of transcription/chromatin factor binding or histone modification … WebNature, 2011) were conducted using ChIP-Seq data from two cell types (K562 and H1 ESCs), using all ChIP-seq tracks available at the time. The ChIP-Seq tracks employed … WebMay 30, 2014 · Conversely, ChIP-seq data can be used to create gene sets against which other experimental data sets can be tested for significant enrichment, including other ChIP-seq data (5, 6). Gene set enrichment tests can generally be classified as competitive (2, 7, 8), self-contained or a hybrid (9, 10), as discussed by Efron and Tibshirani in . The ... literary cars