WebCircWHSC1 functioned as the sponge for miR-142-3p, which directly targeted HOXA1. Inhibition of miR-142-3p ameliorated the effects of circWHSC1 knockdown on HCC cell proliferation and metastasis. Moreover, miR-142-3p overexpression restrained the growth and motility of HCC cells, with HOXA1 elevation reversing the impacts. WebDec 31, 2024 · We found that circWhsc1 was enriched in neonatal mouse hearts, particularly in cardiac ECs, and was further upregulated both in ECs and EC-derived EVs under hypoxic conditions. When cocultured with hypoxia-preconditioned neonatal ECs or their secreted EVs, both neonatal and adult CMs exhibited an increased proliferation rate …
LncRNA SNHG14 Promotes Progression of Ovarian Cancer by …
WebCompared with the group transfected with control vector, overexpression of circWHSC1 in CAOV3 increased cell growth (a), reduced cell apoptosis (c), increased cell migration (e) and invasion rate (g). Webboth circWHSC1 overexpressed and down-regulated cell lines were further selected with 2 μg/mL puromycin. The sequences of circWHSC1 and shRNA can be found in Additional file 1:TableS3. MTT assay The circWHSC1 overexpressed and down-regulated cells with control group were counted and seeded in 96-well plates. 0h, 24h, 48h and 72h after … bioware.com dragon age 2
CircWHSC1 promotes ovarian cancer progression by
WebJan 6, 2024 · CircWHSC1 functioned as the sponge for miR‐142‐3p, which directly targeted HOXA1. Inhibition of miR‐142‐3p ameliorated the effects of circWHSC1 knockdown on … WebCircWHSC1 functioned as the sponge for miR-142-3p, which directly targeted HOXA1. Inhibition of miR-142-3p ameliorated the effects of circWHSC1 knockdown on HCC cell … WebCircWHSC1 overexpression promoted the proliferation, migration and invasion of endometrial cancer cells and decreased apoptosis. CircWHSC1 knockdown had the opposite effect. CircWHSC1 overex-pressed nude mice showed increased tumorigenicity. Bioinformatics predicted that circWHSC1 binds to miR-646, which was confirmed using … bioware.com login